A few users have reported a major problem to me when using Kodi on iOS 10. From what I am told is that audio via AirPlay does not work. Now this happened on iOS 9 with Kodi as well. And if you don’t remember the developers did not fix it till a jailbreak was released. This is due to Kodi being meant to run on Jailbroken devices and not unjailbroken devices. 

I hope that the developers see that Kodi has a very large demand to be on unjailbroken devices. So for now if your a big Kodi user don’t update to iOS 10.